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Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene deffenses

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Since IGF-1R and IR are structurally similar and IGF-1 can bind to IR with lower affinity, IGF-1 could cause hypoglycemic effects if it can freely access to the IR [101,102]

But if youre completely put off by needles, you could discuss the possibility of switching to an oral alternative, as some providers offer it in oral forms: tablets, lozenges, and troches